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Can you live a long life with PBC? Advances in treatment have extended the life expectancy in the past many years. The average survival from diagnosis for a patient with PBC who is asymptomatic is 16 years, while that of patients with symptoms is 7 1/2 years.
How do you test for PBC? Once PBC is suspected, a blood test to check for antimitochondrial antibody (AMA) is done. This test is positive in nearly all people with PBC. A liver biopsy, where a small sample of liver tissue is removed with a small needle can help confirm the diagnosis.
Is PBC a terminal? PBC is a chronic, progressive cholestatic liver disorder that is caused by an autoimmune attack on small bile ducts and that occurs almost exclusively in women aged 35 to 70. PBC typically progresses to a terminal stage over 15 to 20 yr.
Does liver transplant cure PBC? Orthotopic liver transplantation (OLT) remains the definitive treatment for decompensated liver disease secondary to PBC. However, despite its potential benefit, there is no evidence that UDCA improves graft or patient survival in recurrent PBC.
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